5-Amino-1MQ

5-Amino-1MQ is a small, selective, membrane permeable molecule that is an NNMT inhibitor, and an ideal ingredient for anti-obesity medication. 5-amino-1MQ is a derivative of methylquinolinium which has exhibited a high efficacy in NNMT inhibition, cell viability, and membrane permeability. This NNMT inhibitor could be used to prevent adipogenesis and type II diabetes, and reverse diet-induced obesity as a result of increased intracellular NAD+ and SAM.

5-Amino-1MQ taken in conjunction with a low calorie or ketogenic diet can result in increase fat burning/body fat consumption over time. It is recommended to commit to 2-3 months of 5-Amino to see results. Consume once per day in the morning.

5-amino-1MQ blocks an enzyme that plays a role in energy utilization. It functions to actively increase basal metabolic rate (BMR). This increase in BMR is often accompanied by an  increase in appetite. For 5-amino-1MQ to work most effectively for fat loss, patients taking the drug should continue to operate at a caloric deficit, which means you consume fewer calories than you burn. Furthermore, patients can expect to see improved physical performance approx. two weeks after starting the medication.

5-amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as ‘the longevity gene’ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

This means that 5-amino-1MQ allows your body to burn fat for energy while maintaining muscle mass preferentially. 5-amino-1MQ is both safe and effective for reversing and preventing diet-induced obesity. It is a potentially superior treatment option for individuals suffering from (or who are at risk for) type II diabetes and other metabolic comorbidities to obesity. Furthermore, the activation of SIRT1 by an increase in NAD+ suggests 5-amino-1MQ is a good option for patients who are looking to develop a comprehensive anti-aging  protocol.